Siegfried Weisenburger's research profile
Our paper entitled “Mechanism of sensor kinase CitA transmembrane signaling” has been published in Nature Communications. We have employed an integrated structural biology approach combining solid-state NMR, crystallography, solution NMR, and distance measurements to elucidate the transmembrane signaling mechanism of the membrane-bound histidine kinase CitA. Central to our study is […]
Our patent on “Hybrid multi-photon microscopy” has been granted. You can download the patent documentation here: https://patents.google.com/patent/US11808702B2/
Our patent application on “Hybrid multi-photon microscopy” has been published. Download the patent here: https://patents.google.com/patent/WO2020160229A1/
As a small project, I wanted to make a home-built photography lens. There are a few boundary conditions for the project: Constructed from off-the-shelf optics and opto-mechanics components to avoid manufacturing of custom parts. Should be compatible with Nikon f-mount (because I have a Nikon DSLR). About 100 mm focal […]
Our paper about HyMS microscopy is featured as a Research Highlight editorial in Nature Methods: https://doi.org/10.1038/s41592-019-0442-7
Our paper entitled “Volumetric Ca2+ Imaging in the Mouse Brain using Hybrid Multiplexed Sculpted Light (HyMS) Microscopy” has been published. We have developed a modular platform named Hybrid Multiplexed Sculpted Light (HyMS) microscopy featuring a systems-wide design paradigm that maximizes the acquisition volume size and speed while maintaining fidelity for […]
COLD microscopy is featured in the “Super-resolution microscopy” Nature Collection as a methodology exemplifying new and interesting applications of super-resolution microscopy.
I’ve written a review article about volumetric optical imaging of neuronal activity. You can read the preview here or the arXiv preprint.
Our publication about COLD microscopy is mentioned as a ‘Method to Watch’ in the current issue of Nature Methods in a special feature Structure via super-resolution by Natalie de Souza.
We were watching the solar eclipse in the United States together with the lab. Here are some pictures of me using one of the most important tools in an optics lab to visualize the sun – an ND filter.
I was awarded a Leon Levy Fellowship in Neuroscience from the Leon Levy Foundation.
I received the Young Scientist Award of the German Society for Applied Optics (DGaO) in Dresden last week.
I will be giving a talk about my research at the BioDIP in Dresden on June 9th in the morning.
I gave a talk about Large Volume Functional Imaging in the Mouse Brain at the Rockefeller University Neuroscience retreat at Stone Barns last Monday.
Our publication about the scanned temporal focusing microscope is part of Nature’s paper collection “Deep imaging of live tissue”.
